implants – TechConnect Briefs

Spectroscopical and Structural Studies of Sol-gel Reservoirs used as Implants in the Delivery of Dopamine to the Central Nervous System

Lopez T., Esquivel D., Ascencio J., Odriozola J.A., Gonzalez R.D., Tulane University, US

The stabilization of dopamine used in the treatment of Parkinsons is a pressing problem. When dopamine is applied systemically. destabilization may occur following penetration through the blood brain barrier (BBB). In order to circumvent this [...]

Multicomponent Coatings Improve the Biocompatibility of Load-bearing Implants

Chissov V.I., Reshetov I.V., Frank G.A., Levashov E.A., Shtansky D.V., Filushin M.M., Efremov G.D., Sukharev S.S., P.A.Hertzen Moscow Research Oncological Institute, RU

New implants are studied in vivo under the conditions, when the replaced defect is located on the bone, which accomplishes motions with the large amplitude and with the large load.Three types of implants were placed [...]

Effect of Microtopography and Cell Concentration on T Lymphoid Cell Migration during in vitro Extravasation Process

Prina-Mello A., Volkov Y., Prendergast P.J., Trinity College, IE

The locomotion of leukocyte cells has been proved to be influenced by microtopographical patterns with and without surface chemistry [Prina-Mello et al., 2003, Lo et al., 2000]. In this study, parallel grooves were microfabricated on [...]

Reconstruction of Load-Bearing Defects in Oncology by Using Nanomodification of Implants

Chissov V.I., Reshetov I.V., Levashov E.A., Shtansky D.V., Filushin M.M., Sukharev S.S., Bashkova I.A., Moscow Research Oncological Institute, RU

By means of nanotechnological approach different coating procedures enlarging biocompatibility factors of implants were developed. The well-known materials – titanium plates are used as substrates supporting structures. Depending on the construction type (stable or rolling) [...]