heart – TechConnect Briefs

Polyethylene-oxide (PEO) linear nano-polymer directly stimulates endothelium and protects myocardium from focal ischemia-reperfusion injury via eNOS pathway in rats

Uryash A., Arias J., Wu H., Adams J.A., Mount Sinai Medical Center, US

Medical grade Nano-polymers (NP) used to enhance circulation, drug and gene delivery. Injection of Polyethylene-oxide (PEO) increase tissue perfusion and decrease mean blood pressure in animal models. Polyethylene-oxide (PEO) NP’s ultra high molecular weight (2-5 [...]

A search of superparamagnetic iron oxide-myoglobin as potential nanoparticle based magnetic resonance imaging marker in mouse heart imaging

Sharma R., Haik Y., Chen C-J., FAMU-FSU College of Engineering, US

Superparamagnetic iron oxide (Fe2O3) has emerged as potential MRI contrast agent in whole animal imaging to localize the site of clinically important physiological damage such as ischemia, angiogenesis, oxygen insufficiency, immuno-deficiency [1, 2]. We achieved [...]