gold nanoparticles – Page 4 – TechConnect Briefs

Optimizing Instrument Operation and Data Processing for Single Particle Inductively Coupled Plasma Mass Spectrometry Measurement of Gold Nanoparticles

Liu J., Murphy K.E., MacCuspie R.I., Winchester M.R., National Institute of Standards and Technology, US

In recent years, inductively coupled plasma mass spectrometry (ICP-MS) operated in time-resolved analysis (TRA) mode has merged as a promising analytical tool capable of both sizing and counting metal containing nanoparticles in aqueous suspensions. In [...]

EGF conjugated gold and silver nanoparticles for imaging EGFR over-expressing cells

Lucas L.J., Hewitt K.C., Dalhousie University, CA

Purpose: To create and validate a novel SERS-based nanoprobe for optical imaging of the epidermal growth factor receptor (EGFR). Experimental Design: Gold and silver nanoparticles (Au/AgNPs) were synthesized and coupled to epidermal growth factor (EGF) [...]

Sequential Surface Functionalization by Polyoxometalates and Lysine Renders Non-toxic Gold Nanoparticles Strong Antibacterial Agents

Daima H.K., Selvakannan P.R., Bhargava S.K., Bansal V., RMIT University, AU

Gold nanoparticles (AuNPs)are considered as biocompatible and important component for biomedical applications. In current study, AuNPs were synthesised using tyrosine amino acid mediated reduction of gold ions. These nanoparticles were functionalised with two polyoxometalates (POMs) [...]

Gold nanoparticles as a tool to detect UTI and their cytotoxic effects in DU-145 cells

Vedantam P., Tzeng J., Brown A., Podia R., Staley K., Rao A., Clemson University, US

The abstract includes a brief description of how two different kinds of E.coli can have different binding specificities and detection of such organisms with sugar functionalized nanoparticles can be used as a biodiagnostic technique.

A Novel High Yield Process for Gold Sulfide Nanoparticle Synthesis via Shifting Equilibrium of Self-Assembly Reaction

Patel D., James K., Zhang G., Gobin A.M., University of Louisville, US

This project is focused on the scale up of gold-gold sulfide (GGS) nanoparticles with desired near infrared peak (nIR) that can be used for therapeutic applications. By combining published methods for 1-step self-assembly of GGS [...]

Highly Stable PEGylated Gold Nanoparticles in water: Applications in biology and catalysis

Rahme K., Nolan M.T., Doody T., McGlacken G.P., O’Driscoll C., Holmes J.D., Notre Dame University (NDU), LB

Gold nanoparticles (Au NPs) with diameters ranging between 5-60 nm have been synthesised in water. Functionalised polyethylene glycol-based thiol polymers (mPEG-SH) were used to stabilise the pre-synthesised Au NPs. The grafting density of different PEG [...]

Cell Culture Media elicit a different dynamic Formation of Protein-NP Complexes: Effects on the Cellular Response

Sabella S., Maiorano G., Sorce B., Brunetti V., Malvindi M.A., Cingolani R., Pompa P.P., Italian Institute of Technology, IT

We show that the dynamics of proteins-NP interactions are differently mediated by different cellular media, which are the liquid environments where NPs encounter cells. We used, as a model, spherical NPs (citrate-capped gold nanoparticles, AuNPs) [...]

In vivo nanotoxicity assessment: the role of size, surface coating, nanostructuration and dose-metrics

Vecchio G., Galeone A., Brunetti V., Maiorano G., Malvindi M.A., Sabella S., Cingolani R., Pompa P.P., Italian Institute of Technology, IT

The growing use of nanomaterials in commercial goods and as novel carriers for drug delivery is generating increasing questions about possible risks for human health and environment, due to the lack of an in-depth assessment [...]

Celastrol-Based Nanomedicines as Modulators of Neuroinflammation

Boridy S., Hutter E., Soliman G., Maysinger D., McGill University, CA

Chronic inflammation plays a pivotal role in promoting disease pathology in the central nervous system (CNS). Microglial cells are the main innate immune effector cells in the CNS and orchestrate these neuroinflammatory reactions that ultimately [...]

New Generation Hybrid Plastics Functionalised by Nanogold and Nanosilver

Pobedinsky M., Johnston J.H., Victoria University of Wellington, New Zealand, NZ

This paper reports on the synthesis of a new generation of hybrid plastics comprising polyurethane and nylon with gold or silver nanoparticles respectively, in a synergistic way. The gold and silver nanoparticles are prepared in-situ, [...]