gold nanoparticle – Page 3 – TechConnect Briefs

Chip-Based Energy Transfer System between Quantum dots and Gold Nanoparticles for Analysis of Protein Glycosylation

Kim H-S, Kim Y.P., Park S., Oh E., Oh Y.H., Oh E., Oh Y.H., Kim H-S, Kim Y.P., KAIST, KR

Protein glycosylation is one of the most essential processes in the living systems, and often is a major target for developing therapeutics and diagnosis. We have developed a chip-based energy transfer system between quantum dot [...]

Multiplexed Proteolytic Enzyme Assay Based on Energy Transfer between Quantum Dots and Gold Nanoparticles

Oh Y.H., Kim H-S, Kim Y.P., Kim H-S, Kim Y.P., Korea Abvanced Institute of science and Technology, KR

Proteases are key enzymes that regulate both normal and malignant tumor progress. Evaluating these enzymes and their inhibitors, therefore, has a great potential to diagnostics or therapeutic treatment against specific diseases or disorders. We have [...]

Gold nanoparticle-based miniaturized NSET Probe for rapid and ultra-sensitive detection of toxic metals in soil, water and fish

Ray A., Ray P.C., Darbha G.K., Ray A., Ray P.C., Jackson State University, US

Contamination of the environment with toxic metals like mercury and arsenic have been an important concern throughout the world for decades. Human exposure to high Hg or As levels can harm the brain, heart, kidneys, [...]

Gold Nanoparticles as Colourants in High Fashion Fabrics and Textiles

Johnston J.H., Richardson M.J., Burridge K.A., Kelly F.M., Victoria University of Wellington, NZ

Gold nanoparticles which exhibit different colours due to surface plasmon resonance scattering effects are used here as stable colourants on wool and synthetic fibres. This provides the exciting opportunity to link nanoscience with high value [...]

Adsorption of Colloid Gold Nanoparticles on Charged Surface

Tzeng S-D, Luo C-S, Gwo S., Lin K.-J., National Chung Hsing University, TW

Colloid gold nanoparticles have many important applications, such as bio-molecular sensors and electronic devices. To fabricate the devices, one of the most significant processes is to assemble the gold nanoparticles on surface. In this work, [...]

Biodistribution and Toxicity of Nanomaterials In Vivo: Effects of Composition, Size, Surface Functionalization and Route of Exposure

Harper S.L., Maddux B., Hutchison J., Tanguay R.L., Oregon State University, US

Given the anticipated growth of the nanotechnology industry and the deficiency of toxicological information, there is an obvious need for rapid, relevant and efficient testing strategies to evaluate the biological activity and toxic potential of [...]

Differential lethality of gold nanoparticles is associated with immunogenecity

Huang G.S., Chen Y-S, Yeh H-W, National Chiao Tung University, TW

To obtain antibodies specifically recognizing gold nanoparticles (GNPs) BALB/C mice were immunized by weekly intra-peritoneal injection of adjuvant-emulsified 5 nm, 8 nm, 12 nm, 17 nm, and 37 nm GNPs. Mice injected with 8 nm, [...]

Fast and Easy Detection System of Protein Glycosylation by Using Resonant Energy Transfer between Nanoparticles

Oh E., Lee D., Kim H-S, Korea Advanced Institute of Science and Technology, KR

We construct the new glycosylation detection system using Resonance Energy Transfer (RET) between gold nanoparticles (AuNPs) and semiconductor quantum dots (QDs). RET can be induced by biomolecular interactions between concanavalin A (conA)-conjugated AuNP (conA-AuNP) as [...]

Label Free Colorimetric Detection of Single Nucleotide Polymorphisms in Pcr Amplified Genomic DNA

Li H.X., Rothberg L.J., University of Rochester, US

Analysis of DNA is increasingly important in clinical diagnosis, pathology and genetics1, 2. Single nucleotide polymorphisms (SNPs) in genomic DNA are known to be responsible for a number of hereditary conditions3 and cancers4. Nearly all [...]

Rapid DNA Sequence Identification based on Electrostatic Interactions with Unmodified Gold Nanoparticles

Li H.X., Rothberg L.J., University of Rochester, US

Sequence-specific detection of DNA play more and more important role in clinical diagnosis and molecular biology research. Most assays identify specific sequence through hybridization of an immobilized probe to the target analyte after the latter [...]