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HomeKeywordsDNA microarrays

Keywords: DNA microarrays

Novel alternative, multistranded, plasmid, and helical transitional DNA and RNA microarrays: the next generation of nucleic acid microarrays

Gagna C.E., Lambert W.C., New York Institute of Technology, US
Novel multistranded and alternative DNA, RNA and plasmid microarrays have been developed that allow for immobilization of intact, nondenatured nucleic acids. Biomolecules are anchored onto a solid support and can move freely, while researchers experiment [...]

A method for the highly parallel analysis of gene expression of single cells

Meuleman W.R.A., Milner N., Lueerssen D.W.K., Southern E.M., Oxford Gene Technology, UK
Presented is a method for carrying out rapid single cell gene expression analyses on a large number of cells in parallel. The entire analysis is carried out on a DNA microarray. We demonstrate single molecule [...]

Rapid Isothermal Amplification and Multiplexed Surface Detection of Short DNA Sequences

Tan E., Han Y., Kniazeva E., Buechel M., Erwin B., Niemz A., Keck Graduate Institute, US
We have coupled a novel isothermal amplification method for short oligonucleotides (EXPAR) with solution and surface-based detection involving DNA-functionalized gold nanospheres. In these assays, a trigger oligonucleotide is exponentially amplified and converted to a reporter [...]

Direct Parallel Patterning of Multiplex DNA and protein arrays

Rozhok S., Amro N., Fragala J., Levesque T., Nelson M., NanoInk Inc, US
Multiplex DNA and protein arrays can be routinely generated on glass or metal-coated substrates via Dip-Pen Nanolithography (DPN) using new commercially available DPN accessories like multiple pen arrays and inkwells.

Molecular Simulation of DNA Microarrays – an Application of 2D particle mesh Ewald algorithm

Watanabe T., Kawata M., Nagashima U., National Institute of Advanced Industrial and Science and Technology, JP
We have developed the two-dimensional particle mesh Ewald (2D-PME) algorithm for molecular dynamics (MD) simulation, and applied it to have knowledge of the behavior of DNA and its interaction on microarrays, which crucial in the [...]

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