A method for the highly parallel analysis of gene expression of single cells

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Presented is a method for carrying out rapid single cell gene expression analyses on a large number of cells in parallel. The entire analysis is carried out on a DNA microarray. We demonstrate single molecule resolution without the use of PCR, allowing us to quantitatively analyse high as well as low levels of gene expression. Because of the parallel nature of the method, individual cells within a population can be compared rapidly and conveniently.

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Journal: TechConnect Briefs
Volume: 3, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 3
Published: May 20, 2007
Pages: 296 - 299
Industry sector: Sensors, MEMS, Electronics
Topic: Micro & Bio Fluidics, Lab-on-Chip
ISBN: 1-4200-6184-4