conjugation – TechConnect Briefs

Biomolecular activity switch: an application of metallic nanoparticle plasmon resonance

Alper J., Wijaya A., Crespo M., DeFlores L., Tokmakoff A., Hamad-Schifferli K., Massachusetts Institute of Technology, US

Specific external control of biomolecular activity is a critical step in harnessing the power of nature’s molecular machinery. We propose and demonstrate one control method, a biomolecular activity switch. Since proteins are the primary macromolecule [...]

Hybrid Nanomaterials for Active Electronics and Bio-Nanotechnology

Wang X., Pandey R.R., Lake R., Ozkan C.S., University of California Riverside, US

We describe self assembly processing of functional carbon nanotubes using single strand deoxyribonucleic acid (DNA) and peptide nucleic acid (PNA) fragments. Previous research has shown the self assembly of carbon nanotubes to quantum dots via [...]

Conjugation of DNA to Streptavidin-coated Quantum Dots for the Real-time Imaging of Gene Transfer into Live Cells

Kim J.K., Lim S.H., Lee Y., Shin Y.S., Chung C., Yoo J.Y., Chang J.K., Digital Bio Technology, Co, KR

We have developed the method for the conjugation of biotinylated DNA to streptavidin-coated quantum dots (QDs). QD-DNA conjugates and a highly sensitive fluorescence imaging technique are adopted to visualize gene transport across the membrane of [...]