circulating tumor cells – TechConnect Briefs

Analysis and Simulation of Rare Cell Detection and Size Based Profiling Using Coupled Micro-Hall Detectors

Gajasinghe R.W.R.L., Gabriel A., Tigli O., University of Miami, US

In this paper, we propose a method that uses magnetic nanoparticles (MNPs) to detect, and also estimate sizes of rare cells using Hall-effect. Rare cells labeled with MNPs are detected in-flow using a pair of [...]

Capture of circulating tumor cells (CTCs) using a novel micro-device

Ranjan S., Yong Z., National University of Singapore, SG

Circulating tumor cells (CTCs) are metastatic cells that are detached from a tumor and are found in the blood of cancer patients. The presence of CTCs in the blood indicates the metastatic stage of cancer, [...]

Lab-on-chip for the isolation and characterization of circulating tumor cells

Laureyn W., Liu C., O’Sullivan C.K., Llaudet E., Nilsson O., Drese K.S., Roeser T., Ritzi M., Hauch S., Albert W., Borgen E., Nygren A.O.H., IMEC, BE

A consortium of 7 European partners has undertaken the challenging task to develop a microfluidic system (μTAS) capable of the isolation/enrichment and consecutive RNA/DNA characterization of circulating tumor cells (CTCs), to be used as a [...]

Circulating Tumor Cells: Capture with a Micromachined Device

Mohamed H., Murray M., Turner J.N., Caggana M., New York State Department of Health, US

The isolation and analysis of circulating tumor cells (CTCs) from blood is the subject of intense research. Tests to detect metastasis are available but progress is hampered by the lack of tumor-specific markers and predictable [...]