boundary element methods – TechConnect Briefs

Fast Methods for Biomolecule Charge Optimization

Bardhan J.P., Lee J-H., Kuo S.S., Altman M.D., Tidor B., White J.K., Massachusetts Institute of Technology, US

We report a Hessian-implicit optimization method for linearly constrained quadratic programs. Our research focuses on the energetics of protein-protein interactions, and this method was developed to quickly solve the charge optimization problem: given a ligand [...]

Modeling of Microfluidic Devices Using Scalable Algorithms

Stals L., Old Dominion University, US

We present parallel algorithms for the solution of micro uidic equations. The algorithm consists of the multigrid method in combination with adaptive finite elements. These methods give good algorithmic and parallel scalability and are thus [...]

A Fast Stokes Solver for Generalized Flow Problems

Ye W., Wang X., White J.K., Massachusetts Institute of Technology, US

Computing drag forces on geometrically complicated 3-D micromachined structures, such asan entire comb resonator, is a challenging problem. The recently developed FastStokes solver, based on precorrected-FFT accelerated iterative methods, has made analyzing such problems much [...]

Numerical Fracture Analysis of MEMS Devices

Tayebi A.K., Tayebi N., Tayebi A.K., Tayebi N., Case Western Reserve University, US

Non-conventional finite element analysis (FEA) based on linear elastic fracture mechanics (LEFM) is applied to fractured MEMS specimens with notches. The objective of this paper is to test the applicability of LEFM at mesoscale and [...]

A Fast Integral Equation Technique for Analysis of Microflow Sensors Based on Drag Force Calculations

Aluru N.R., White J.K., Massachusetts Institute of Technology, US

It is well known that MEMS based microfluidic devices operate in very low Reynolds number regime (Re < 1). Analysis and design of such microfluidic devices requires the solution of incompressible viscous fluid flow or [...]