biomarkers – Page 2 – TechConnect Briefs

Detection of Cancer Related DNA Nanoparticulate Biomarkers and Nanoparticles in Whole Blood

Heller M.J., Krishnan R., Sonnenberg A., University of California San Diego, US

The ability to rapidly detect DNA nanoparticulate biomarkers and drug delivery nanoparticles directly in blood is a major challenge for early disease detection and nanomedicine. We now show that a microarray dielectrophoretic (DEP) device can [...]

Integrated Microfluidic Device with an Electroplated Palladium Decoupler for Electrochemical Detection of the 8-hydroxydeoxyguanosine (8-OH-dG) DNA Adduct

Dawoud A.A., Kawaguchi T., Jankowiak R., Iowa State University, US

More sensitive and reliable microfluidic devices are needed for the detection of the 8-hydroxy-deoxyguanosine (8-OH-dG) DNA adduct, one of the most frequently used biomarkers reporting on oxidative stress. Therefore, we have developed a capillary electrophoresis [...]

Rapid Detection of Multiple Myeloma using a microfluidic platform

Kaigala G., VanDjinkin J., Taylor B.J., Backhouse C.J., Pilarski L.M., University of Alberta, CA

MM has a unique molecular signature and is well suited as a model system for performing analysis on microchips. MM multiplex genetic analysis for clonotypic signatures and genetic abnormalities offers the possibility for genetic profiling [...]