biochips – TechConnect Briefs

Computational Modeling and Simulation of Microfluidic Biochips for Parallel Biomolecular Synthesis

Kan H-C, National Center for High-performance Computing, TW

In this study, a novel microfluidics based biochip has been developed by the aid of analytical modeling and numerical simulation efforts for the purpose of massively parallel oligonucleotude-DNA (oDNA) syntheses. The microfluidic biochip consists of [...]

Use of Magnetoresistive Biochips for Monitoring of Pathogenesis Microorganisms in Water through Bioprobes: Oligonucleotides and Antibodies

Martins V.C.B., Fonseca L.P., Ferreira H.A., Graham D.L., Freitas P.P., Cabral J.M.S., Instituto Superior Técnico, PT

Magnetoresistive biochips have been integrated with success in a microtechnology engineered set-up for the development of a portable analytical device, characterized by low-cost with high sensitivity and selectivity of immunodetection and biomolecular methods [1, 2]. [...]

Circulating Tumor Cells: Capture with a Micromachined Device

Mohamed H., Murray M., Turner J.N., Caggana M., New York State Department of Health, US

The isolation and analysis of circulating tumor cells (CTCs) from blood is the subject of intense research. Tests to detect metastasis are available but progress is hampered by the lack of tumor-specific markers and predictable [...]

Towards Microelectrofluidic System (MEFS) Computing and Architecture

Dewey A., Fair R.B., Jopling J., Ding J., Zhang T., Cao F., Schreiner B., Pollack M., Duke University, US

This paper presents the rationale, design, and simulation of next-generation microelectro fluidic system computational architectures for the emerging field of bioinformatics. Current microelectro fluidic processors (e.g. biochips) have largely dedicated architectures supporting relatively specialized applications. [...]