biochip – TechConnect Briefs

Point-of-Care (POC) Micro Biochip for Cancer Diagnostics

Nunna B.B., Lee E-S, New Jersey Institute of Technology, US

American cancer society stated that a total of 1,685,210 new cancer diagnosed cases out of which 595,690 deaths from cancer are expected to be reported in the United States of America in 2016. Unfortunately Cancer [...]

A novel on chip analysis of dissolved Hg(II) in drinking water

Deshpande K., Mishra R.K., Pal S., Danielsson B., Willander M., Bhand S., Birla Institute of Technology & Science, Pilani-Goa Campus, IN

A novel biochip based detection for determination of ultra trace mercury (Ii), lead(II) and cadmium (II)in drinking water. High through put analysis, low sample volume, high sensitivity and rapid analysis is the hallmark of the [...]

Phosphate recognition using multilayer charged thin films containing zirconium (Zr) ions for biochip applications

Lee M., Kim J.H., Kim N., Kim S-H, Kim J.H., Kim N., Kim S-H, Shin C.-J., Koh K., Kim J.H., Kim N., Kim S-H, Ajou University, KR

The phosphate residue plays an important role as not only the structural component of DNA and lipid but also the activation signal of protein in the cellular signaling pathways. Therefore, the selective recognition for the [...]

A Micromachined Sparse Cell Isolation Device: Application in Prenatal Diagnostics

Mohamed H., Turner J.N., Caggana M., Wadsworth Center, New York State Department of Health, US

The isolation of fetal cells from maternal circulation is the subject of intense research. Fetal cells can be isolated using several enrichment methods, however no technique to specifically isolate and use them for genetic diagnosis [...]

Biomolecular diagnostics by a magnetic lab-on-a-chip

Brückl H., Eggeling M., Heer R., Nöhammer C., Schotter J., ARC Seibersdorf Research GmbH, AT

Compared to the established fluorescent labeling method, the use of magnetic markers in biochip sensors has important advantages with respect to the detection of biomolecules at low concentrations. Additionally, the direct availability of an electronic [...]

Binding Efficiency Improvement of Antibody to Antigen on Mixed Self-Assembly Monolayers

Wu C-L, Lin Y-W, Hsu Y-L, Tseng F-G, Chieng C-C, National Tsing Hua University, TW

We make a mixed Self Assembly Monolayer for improve binding efficiency antibody, this method provide s stereo advantage and didn't need to modify antibody by moelcuar biology ono by one.

Pneumatic Regulation of Bi-Directional Fluid Flow in Microchannels

Wan Y-M., Wang S-H., Yao N-K., Chen C., Hung L-Y., Wang S-H., ITRI, TW

This paper presents a modeling of airflow inside micro-tunnel for fluid pumping. By utilizing unidirectional air servo system, fluid flow can be regulated within microchannels. The operation of servo system is controlled with multiple nozzles. [...]