alternating copolymer – TechConnect Briefs

Folic Acid Conjugated Polymer as a New Active Tumor Targeting Drug Delivery Platform

Li X., Szewczuk M.R., Malardier-Jugroot C., Royal Military College of Canada, CA

Nanotechnology has been extensively exploited to improve conventional cancer therapy in the recent years1. The designed nanocarriers allow drug to be delivered to cancer cells specifically with prolonged circulation time and controlled drug release2–4. In [...]

Conformation of pH Responsive Alternating Copolymers and Self-Assembly in Nanoarchitectures

Chan A.S.W., Groves M., Malardier-Jugroot C., Royal Military College of Canada, CA

Our research focuses on the characterization of the association and the properties in aqueous solution of nanostructures composed of amphiphilic alternating copolymers. These copolymers are composed of a pH sensitive hydrophilic group, maleic anhydride alternating [...]

Characterization of a Novel Self-Association of an Alternating Copolymer into Nanotubes in Solution

Malardier-Jugroot C., van de Ven T.G.M., Whitehead M.A., McGill University, CA

The characterisation of the association of an alternating copolymer was performed using theoretical methods (quantum mechanics and molecular mechanics) and experimental methods (cryo-Transmission Electron Microscopy, Neutron Reflectivity and Neutron Scattering). The most stable conformation obtained [...]