Zhu P. – TechConnect Briefs

Monte Carlo Simulation of Electrochemical Detection of Redox Molecules with Nanoscale Redoxcycling

Zhu P., Iwahara S., Nakazato K., Uno S., Ritsumeikan University, JP

Biosensors that can detect minute quantities of important redox molecules in the human body are increasingly gaining attention nowadays. Currently, electrophoresis,fluorescence and amperometric detection methods are the common techniques used for such purpose. The previous [...]

Utility of Customized Targeted PEG Linkers for the delivery of oligonucleotides without the use of transfection reagents

Zhao H., Reddy P., Xia J., Wang M., Sapra P., Bandaru R., Belen Rubio M., Wu D., Zhu P., Filpula D., Greenberger L.M., Horak I.D., Enzon Pharmaceuticals, Inc., US

Delivery of LNA oligonucleotides using Customized Targeted PEG linkers has improved the in vitro cellular uptake into cancer cells. Customized Targeted PEG linker-LNA conjugates can knock down target mRNA in a concentration dependent fashion with [...]