Yilma A.N. – TechConnect Briefs

Poly-Vinyl Pyrrolidone (PVP)-coated Silver (Ag) Nanoparticles (Ag-PVP): a Potential to Regulate Chlamydia trachomatis Inflammation

Yilma A.N., Singh S.R., Dixit S., Hidat G.G., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Previously we reported Ag-PVP (5-10 nm) [...]

PLA-PEG as a delivery system for a Chlamydia trachomatis subunit vaccine

Dixit S., Singh S.R., Yilma A.N., Agee R., Dennis V.A., Alabama State University, US

We hypothesize that M287 encapsulated in PLA-PEG will provide for its slow controlled release and thus enhance its capacity to induce immune responses in mice.

Smaller sizes of Ag-PVP Nanoparticles Control Inflammatory Responses, and Reduce CD80 and CD86 Expression Levels, in Macrophages Infected with Chlamydia trachomatis

Yilma A.N., Singh S.R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is an important cause of sexually transmitted infection that can manifest itself as either acute cervicitis, pelvic inflammatory disease, and more commonly as a chronic asymptomatic infection. Early intervention strategies that can reduce [...]

Evidence of the Anti-inflammatory effect of Silver- polyvinyl Pyrrolidone Nanoparticles (Ag-PVP) in Chlamydia trachomatis infected Macrophages and HeLa Cells

Yilma A.N., Singh S.R., Murtada T.A., Fairley S., Subbarayan P., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is the leading cause of bacterial sexually transmitted diseases (STDs) in the USA, and therefore, of major public health significance. C. trachomatis invades the mucosal surface of the female genital tract consequently triggering [...]