Synthesis and characterization of methoxy poly(ethylene glycol)-O-chitosan-polyethylenimine as a noviral carrier for gene delivery and expression
Yu Y.Y., Wang G., Wang Z., Cai L., Wang G., Wang Z., Yang X., Xu X.H., Xu Z.G., Wan X.P., Wang G., Wang Z., Xu X.H., Xu Z.G., Li Y., Jiang Q., Gao R., Sichuan University, CN
A novel water-soluble chitosan (CS) derivative，methoxy poly(ethylene glycol)-O-chitosan- polyethylenimine(mPEG-O-CS-PEI), was synthesized by grafting polycationic polyethylenimine (PEI) and methoxy poly (ethylene glycol) (mPEG) onto chitosan, the copolymer was characterized and confirmed by 1H-NMR and FT-IR spectra. [...]