Valsesia A. – TechConnect Briefs

SPRi signal amplification by organothiols-nanopattern

Lisboa P., Valsesia A., Mannelli I., Colpo P., Rossi F., JRC-European Commission, IT

A 2D crystalline nanoarray of organothiols has been used for enhancing the detection sensitivity of Surface Plasmon Resonance-based biosensor. In particular, an IgG/AbIgG immunoreaction has been monitored by Surface Plasmon Resonance imaging on nano-patterned surfaces [...]

Nano-Patterned Surfaces Enhance Immunoreaction Efficiency

Valsesia A., Mannelli I., Colpo P., Bretagnol F., Ceccone G., Rossi F., European Commision Joint researcc Center, IT

Biomolecular recognition is a fundamental aspect in the biosensor development. The goal is to immobilize the biomolecule probes in an active state, limiting the non specific adsorption and maximizing their binding site accessibility for the [...]

Functional Nano-Structured Surfaces for Protein Based Sensors

Valsesia A., Meziani T., Colpo P., Lejeune M., Ceccone G., Rossi F., Joint Research Center, European Commission, IT

The reduction of the typical length scale in the creation of patterned surfaces is of high interest in the field of biosensor and bio-interacting materials. During the last few years several researchers explored the influence [...]

Surface Characterization of a Direct, Label-Free Piezoelectric Immunosensor Platform

Papadopoulou-Bouraoui A., Lejeune M., Barrero-Moreno J., Valsesia A., Manso M., Gilliland D., Ceccone G., Rossi F., European Commission - JRC, IT

During this study the QCM (Quartz Crystal Microbalance) crystal surface was functionalized in order to provide active amino groups, and serve as an active platform for antibody immobilization and the development of direct, label-free immunosensors. [...]