Taha M. – TechConnect Briefs

Activation of antigen presenting cells and induction of mucosal antibodies by Chlamydia trachomatis outer membrane peptide encapsulated within PLA-PEG nanoparticles

Dixit S., Taha M., Singh S.R., Dennis V.A., Alabama State University, US

In pursuit of a vaccine against Chlamydia trachomatis, the most reported bacterial sexually transmitted infection, we previously reported that encapsulation of M278, a peptide derived from the major outer protein of C. trachomatis within PLA-PEG [...]

Encapsulation and Characterization of BSA in PLA-PEG Nanoparticles as a Model for Chlamydia trachomatis rMOMP-278 Protein Nanovaccine Delivery System

Taha M., Singh S.R., Moore C., Agee R., Dennis V.A., Alabama State University, US

Chlamydia trachomatis is a major human health pathogen because it is the most reported sexually transmitted disease. There is no effective mucosal vaccine against Chlamydia. One of the major problems of the C.trachomatis vaccine development [...]

Characterization of rMOMP-187 Peptide Encapsulated in PLGA 50:50 Nanoparticles

Taha M., Singh S.R., Butler C., Nyairo E., Dennis V.A., Alabama State University, US

The design of an immunization regimen capable of inducing sustained genital mucosal Th1 response is the current goal for a vaccine for humans to control the severe complications of genital infection by C. trachomatis. In [...]