Petersen S.B. – TechConnect Briefs

Mounting proteins on metal nanoparticles: Statistical analysis of AFM images

Gurevich L., Fojan P., Saxena R.K., Petersen S.B., Aalborg University, DK

In this work we assess the use of atomic force microscopy (AFM) study combined with activity assays, DLS and fluorescent measurements for complex characterization of nanoparticle-protein conjugates. Image processing techniques were used to locate and [...]

Novel Photonic Technique Creates Micrometer Resolution Multi-sensor Arrays and Provides a New Approach to Coupling of Genes, Nucleic Acids, Peptide Hormones and Drugs to Nanoparticle Carriers

Neves-Petersen M.T., Duroux L., Duroux M., Duroux L., Duroux M., Skovsen E., Neves-Petersen M.T., Petersen S.B., Professor, DK

Photonic induced immobilisation is a novel patented technology resulting in spatially oriented and localised covalent coupling of biomolecules onto surfaces. Immobilisation has been achieved for a wide selection of proteins, e.g., human plasminogen, alkaline phosphatase, [...]

Polysaccharide based Nanoparticles and Nanoporous matrices

Fojan P., Schwach-Abdellaoui K., Tommeraas K., Gurevich L., Petersen S.B., Aalborg University, DK

We have successfully obtained good quality SPM images of the gel state of selected polysaccharides. The images reveal a surprisingly flat surface richly decorated with 30-50 nm deep pores. This type of insight we believe [...]

Plasmon-enhanced Fluorescence Detection of Blood Metabolites in Biosensors

Klitgaard S., Rasmussen T., Neves-Petersen M.T., Neves-Petersen M.T., Petersen S.B., Aalborg University, DK

Quick and precise detection of blood metabolites is a key parameter in monitoring and treating critically sick patients. Each analysis requires a certain amount of blood, and especially for babies in neonatal care repeated sampling [...]

New Light Induced Molecular Switch allows Sterically Oriented Micrometer Sized Immobilization of Biomolecules

Snabe T., Neves-Petersen M.T., Fojan P., Klitgaard S., Neves-Petersen M.T., Petersen S.B., Aalborg University, DK

Fundamental knowledge on protein structures and the effect of ultraviolet light on these structures has paved the way for the development of a unique light-based immobilization technology that allows oriented protein immobilization onto micrometer sized [...]