Peng C.L. – TechConnect Briefs

Multi-functional micelles for the combination of chemotherapy and radiotherapy in hepatocellular carcinoma

Shih Y-H, Peng C.L., Luo T-Y, Shieh M.J., National Taiwan University, TW

Hepatocellular carcinoma is the third leading cause of cancer deaths in worldwide. In this study, multi-functional micelles loaded with doxorubicin (Dox) and labeled with the radionuclide rhenium-188 (188Re) were developed to provide the combination of [...]

Synthesis and Photodynamic Efficacy of PAMAM-Photosensitiser Conjugates in Vitro

Peng C.L., Lai P.S., Lai T.-Y., Chiu C.H., Chang C-C, Lai P.S., Lai T.-Y., Shieh M.J., National Taiwan University, TW

Starburst polyamidoamine (PAMAM) dendrimer is a new class of highly branched spherical polymer. Covalent attachment of porphyrin to PAMAM dendrimer may alter the pharmacokinetics, cell targeting, and photophysical properties of photosensitizer. We investigated the uptake, [...]

Application of nanoparticle in photodynamic diagnosis for colorectal cancer

Yang S.J., Peng C.L., Lai P.S., Lin F.H., Shieh M.J., National Taiwan University, TW

Photodynamic medicine is a novel approach for cancer therapy and diagonosis via different photosensitizers and suitable light source. The 5-Aminolevulinic acid (5-ALA) can be converted into protoporphyrin IX (Pp IX ) that can be utilized [...]