Lindall C. – TechConnect Briefs

Reverse Thermoresponsive Polymers for Sustained Delivery of Therapeutic Agents

Mayadunne R., Balachandra A., Gunatillake T., Lindall C., CSIRO, AU

CSIRO has developed thermoresponsive polymers for encapsulation and sustianed release of bioactives. They are stable aqueous solutions over 24 months, easily pass through a 25 gauge needle at room temperature and immediately gel into a [...]

HDCR: A novel method for the diagnostic detection of methylated DNA for blood based cancer diagnostics

Molloy P., Rand K., Ho T., Lindall C., CSIRO, AU

We have developed a novel technique for specific amplification of rare methylated DNA fragments in a high background of unmethylated sequences that avoids the need of bisulphite conversion. The methylation-dependent restriction enzyme GlaI is used [...]