Conjugation of anticancer drugs with novel PEG-containing nanocarrier provides circumvention of drug-resistance mechanisms in vitro and protects of general toxicity in vivo
Kоbylinska L., Panchuk R., Skorohyd N., Senkiv Y., Heffeter P., Berger W., Boiko N., Mitina N., Zaichenko A., Lesyk R., Zіmenkovsky B., Stoika R., Vari G.S., Danylo Halytsky Lviv National Medical University, UA
In the last decade, the development of targeted drug delivery with conjugated nanoparticles brings more drug molecules to the diseased sites, at the same time reducing a systemic drug exposure. Polyethylene glycol (PEG) conjugation is [...]