Carbon Nanotube-based Labels for Sensitive Nucleic Acids Detection
Heng C.K., Lee A.C., Lim T.M., Poenar D., Sheu F.S., Tan S.N., Ye J.S., National University of Singapore, SG
A novel multiple-labelled conjugate with carbon nanotubes (CNTs) to amplify hybridization signal was developed to improve the nucleic acids assay sensitivity. The carboxylated CNTs were functionalized by horseradish peroxidase (HRP) and single-stranded oligonucleotides via diimide-activated [...]