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HomeAuthorsLeclerc M.

Authors: Leclerc M.

Label-free, Fluorescenece Detection of DNA Nanoparticle Scaffolds

Kell A.J., Tan S., Charlebois I., Boissinot M., Simard B., National Research Council, CA
We have developed a nanoparticle-based DNA biosensor that can detect unlabelled ssDNA with good sensitivity (picomolar concentrations). The biosensor makes use of the optical changes of a cationic polymer interacting with ssDNA versus that of [...]

New Ferrocene-Functionalized Cationic Polythiophene For Label-Free Electrochemical DNA Detection

Harding-Lepage P., Le Floch F., Leclerc M., Ho H.-A., Harding-Lepage P., Leclerc M., Université Laval, CA
A specific polycationic polythiophene was discovered in order to identify dsDNA from ssDNA. The main properties of this new polymer are its conformational possibilities associated with photophysics modifications. This conjugated polymer is still subject to [...]

Cationic Polythiophene for Label-Free, Colorimetric and Fluorometric Detection of DNA

Ho H.-A., Leclerc M., Université Laval, CA
In order to respond to new demands and needs in modern medical diagnostics and biomedical research applications, a lot of new DNA detection approaches have been reported. However, most of these methods have the disadvantage [...]

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