Optimizing Quantum Dot-Conjugated Immunoliposomes for Cancer Diagnostics and Targeted Therapeutics
Weng K.C., Noble C.O., Papahadjopoulos-Sternberg B., Chen F.F., Park J.W., UCSF Comprehensive Cancer Center, US
A multifunctional nanoparticle that combines the optical properties of luminescent quantum dots (QDs) and therapeutic modality of immunoliposomes (ILs) has been developed. Carboxylate-derivatized QDs cross-linked with amino- poly(ethylene glycol)-functionalized liposomes were modified with anti-human epidermal [...]