Chen A.M. – TechConnect Briefs

Labile Catalytic Packaging and Delivering of Short Interference RNA to Cancer Cells: Control of Gold Nanoparticles “out” of RNA Complexes

Chen A.M., Taratula O., Wei D., Minko T., He H., Rutgers, The State of New Jersey, US

We report a novel approach to efficiently package and deliver siRNAs with low generation dendrimers by using Au nanoparticles as a “labile catalytic” packaging agent. The Au nanoparticles helped low generation dendrimers to package siRNA [...]

Parallel Pd Nanoribbons by Spontaneous Organization of Pd Nanoparticles

Taratula O., Chen A.M., Zhang J., Chaudry J., Barnerjee I., He H., Rutgers-Newark, The State University of New Jersey, US

A simple solution phase method was used to fabricate Pd nanoribbons which are composed be an array of Pd nanoparticles separated with nanometers gaps. A remarkable feature of this method is that no templates are [...]

Condensation of Therapeutic Oligodeoxynucleotides and Plasmid DNA with PPI Dendrimers and PPI-Modified Gold Nanoparticles

Chen A.M., Nair S.K., Thomas T.J., Thomas T.T., Thomas T.J., Thomas T.T., He H., Rutgers Unverisity, Newark, US

We demonstrated the formation of oligonucleotide nanoparticle in the presence of polypropylenimine dendrimers using total intensity light scattering as well as AFM and TEM. Confocal microscopic analysis showed that the nanoparticles formed with G4 and [...]