University of Notre Dame – TechConnect Briefs

Customized Nanoparticle Probes for Biomedical Imaging, Diagnostics and Therapeutics Applications

Nallathamby P., University of Notre Dame, US

The modular synthetic approach that was developed to design a spectral library of core-shell nanoparticle contrast agents, which will have broad applications in biomedical imaging due to the potential for multi-modal imaging (e.g., fluorescence, MRI, [...]

Modular Nanoparticle Probes for Personalized in Vitro and in Vivo Imaging of Cancer Cell Populations

Nallathamby P.D., Cowden-Dahl K., Roeder R.K., University of Notre Dame, US

The high mortality and poor prognosis for women diagnosed with ovarian cancer is mainly due to late diagnosis. Improved detection of primary tumors and recurrence after chemotherapy is, therefore, crucial to reduce ovarian cancer mortality [...]

Nanomagnet Logic – From Concept to Prototype

Bernstein G.H., Butler K., Li P., Shah F., Siddiq M., Csaba G., Hu X.S., Niemier M., Porod W., University of Notre Dame, US

As the semiconductor industry foresees an inevitable slowing of Moore's Law, many researchers are trying to develop new technologies that go beyond CMOS, in speed, density, cost, or some other desirable metric. Notre Dame has [...]

DNA detection using Laser Transmission Spectroscopy

Li F., Mahon A.R., Barnes M.A., Egan S., Feder J., Lodge D.M., Hwang C.-T., Schafer R., Ruggiero S.T., Tanner C.E., University of Notre Dame, US

Laser transmission spectroscopy (LTS) is a new quantitative and rapid technique for measuring the size, shape, and number of nanoparticles in suspension. We report on the application of LTS as a novel detection method for [...]

Solution Combustion Synthesis of Nano Materials

Dinka P., Mukasyan A., University of Notre Dame, US

In this work we present results on novel approaches related to the solution Combustion (SC) of nano-sized materials. First it was shown that under optimized conditions, SC reactions can be locally initiated and a steady-state [...]

Clocked Quantum-dot Cellular Automata circuits

Kummamurui R., Orlov A., Lent C., Bernstein G., Snider G., University of Notre Dame, US

We present an experimental demonstration of novel Quantum-dot Cellular Automata (QCA) circuits utilizing clocked architecture -a QCA latch and a two-bit QCA shift register. Devices are fabricated using metal tunnel junction technology and operate at [...]

Background Charge Insensitive Single-Electron Memory Devices

Yadavalli K., Orlov A., Snider G., Likharev K., Korotkov A., University of Notre Dame, US

In a Single-Electron Memory Cell (SEMC) one bit of information is represented by the excess or shortfall of a small (¡_1) number of electrons on the floating gate (FG). We present experimental results on the [...]