University of Arizona – TechConnect Briefs

Highly Tunable Surface Plasmons Resonance Using Metal/metal Oxide Hybrid Nanostructures

Khosroabadi A.A., Gangopadhyay P., Norwood R.A., University of Arizona, US

Metal and metal oxide electrodes play a significant role in many cutting edge applications including photonics, membranes, biological supports, sensing, electrochromics, and in various green technologies, such as, photocatalytics, Li-ion batteries and photovoltaics. There is [...]

Applying Plasmon Resonant Coating to Commercial Liposomal Delivery Systems

Knights-Mitchell S.S., University of Arizona, US

Multiple drug-encapsulated liposomes have been successfully marketed as pharmaceuticals within the past two decades. Some of these liposomal drugs have been shown to selectively localize within tumors. However, one limitation is the inability to control [...]

Gold-Coated Liposomes Encapsulating Signaling Molecules for Initiating Cellular Communication

Orsinger G.V., Romanowski M., University of Arizona, US

To better understand the complex communication pathways of the tumor microenvironment, and therefore better design and develop therapies and diagnostics for cancers, experimental methods of probing cellular communication at a single to multi-cell level are [...]

Drug Delivery with Light-Activated Gold-Coated Liposomes

Orsinger G.V., Leung S.J., Knights S.S., Williams J.D., Romanowski M., University of Arizona, US

With the ultimate goal of delivering therapeutic compounds selectively to cancerous or diseased tissues and cells, we have presented liposome-based plasmon resonant nanocapsules. The described biocompatible composite delivery vehicle enables encapsulation and selective release of [...]

Optical Trapping of Gold-Coated Liposomes

Leung S.J., Romanowski M., University of Arizona, US

We recently introduced a nanocomposite material, plasmon resonant gold-coated liposomes, to address unmet needs in area of controlled delivery. Plasmon resonant nanocapsules are created via the deposition of gold onto the surface of 100 nm [...]

Spectrally-Selective Light-Induced Release from Gold-Coated Liposomes

Leung S.J., Romanowski M., University of Arizona, US

To address unmet medical needs in the area of controlled delivery, we recently presented liposome-supported plasmon resonant gold nanoshells. These composite structures are degradable into components of a size compatible with renal clearance, potentially enabling [...]

Self-Assembly of Gold Nanoparticles on E-Beam Nano-Patterns Towards Protein Nanoarray

Powell T., Yoon J-Y, University of Arizona, US

Self-assembly of gold nanoparticles on e-beam nano-patterns towards protein nanoarray. A gold colloid suspensions containing different size nanoparticles, will be dumped in succesion, and the particles will self assemble into proper sized trenches.