Northeastern University – Page 3

Nanotechnology and the Global Poor: United States Policy and International Collaborations

Rodrigues R., Sandler R., Kay W.D., Lodwick T., Northeastern University, US

Nanotechnology and nanomanufacturing have tremendous potential for benefiting the global poor—the approximately 2.7 billion people in the world that live on less that 2 dollars per day (purchasing power parity). For example, nanotechnologies may help [...]

Nanowire Array Technologies for Investigation of Neural Activity

Saha S., Silverberg J., O'Malley D., Menon L., Northeastern University, US

Nanostructures are expected to play a key role in the fundamental investigation of neuronal activity at the nanoscale level. Neurons are complex structures with feature sizes ranging from the millimeter to micron to nanoscale regimes. [...]

Nanotechnology and the Global Poor: United States Policy and International Collaborations

Rodrigues R., Sandler R., Kay W.D., Lodwick T., Northeastern University, US

Nanotechnology and nanomanufacturing have tremendous potential for benefiting the global poor—the approximately 2.7 billion people in the world that live on less that 2 dollars per day (purchasing power parity). For example, nanotechnologies may help [...]

Single Walled Carbon Nanotubes based Three Dimensional Flexible Electronics

Makaram P., Selvarasah S., Chen C., Busnaina A., Dokmeci M.R., Northeastern University, US

Single Walled Carbon Nanotubes (SWNTs) with their superior electrical and mechanical properties are very strong candidates for future electronic applications. CMOS electronics are constantly being scaled down to accommodate more devices. Alternative device geometries are [...]

A Defect Model for Metallic Carbon Nanotubes in Cell-based Logic Circuits

Hashempour H., Lombardi F., Northeastern University, US

Carbon Nanotube based Field Effect Transistors (CNTFET) are promising nano scaled devices for implementing high performance, highly integrated, and low power circuits. The main component of a CNTFET is a single-wall carbon nanotube (SWCNT); its [...]

Economic and Environmental Tradeoffs in SWNT Production

Healy M.L., Tanwani A., Isaacs J.A., Northeastern University, US

Assessment of economic and environmental attributes of nanomanufacturing during process development has significant potential to contribute to the quality and effectiveness of the processes, and will lead to development of competitive, safe and environmentally responsible [...]

Formulation Optimization for the Nanoparticles-in-Microsphere Hybrid Oral Delivery Systems Using Factorial Design

Bhavsar M.D., Tiwari S.B., Amiji M.M., Northeastern University, US

The objective of the present study was to optimize the processing parameters for nanoparticles-in-microsphere hybrid system for oral delivery (NiMOS) and to mathematically relate the process parameters with the selected attribute (particle size) of the [...]

Nanotechnology for Drug Delivery: An Overview

Amiji M.M., Northeastern University, US

Nanotechnology is expected to have a revolutionary impact on biology and medicine. In this paper, I will discuss the role of nanotechnology in development of site-specific drug delivery systems. Polymeric nanoparticles, lipid nanosystems, and self-assembling [...]

Characterization and In Vivo Biodistribution Studies with Poly(Ethylene Glycol)-Modified Thiolated Gelatin Nanoparticles

Kommareddy S., Amiji M.M., Northeastern University, US

Objective: The objective of the current study was to synthesize and modify thiolated gelatin nanoparticles with PEG chains, characterize, and evaluate their long circulating and tumor targeting potentials in vivo in a human breast cancer [...]

Modulation of Intracellular Ceramide using Polymeric Nanoparticles to Overcome Multidrug Resistance in Tumor Cells

van Vlerken L.E., Shenoy D., Duan Z., Seiden M., Mehta S., Amiji M.M., Northeastern University, US

This work describes the formulation of a nanoparticle drug delivery system to co-administer a chemotherapeutic, paclitaxel, and an MDR modulator, C6-ceramide, aimed at overcoming multidrug resistance (MDR) of solid tumors. MDR can arise through several [...]