National Center for Nanoscience and Technology of China

Nanomaterials Employed in Effective Tumor Treatment

Liang X-J., National Center for Nanoscience and Technology of China, CN

Chemotherapy is one of most effective cures to treat different of malignant tumors. Cisplatin is a chemotherapeutic compound commonly used in clinics, however, acquired resistance confines its application in chemotherapeutics. To overcome the acquired resistance [...]

Removing Active Species by Fullerenol in vitro and in vivo

Yin J-J., Lao F., Wamer W-G., Zhao Y., Gao X., Wang P-C, Chen C., Liang X-J., National Center for Nanoscience and Technology of China, CN

We previously demonstrated that gadolinium endohedral metallofullerenol ([Gd@C82(OH)22]n nanoparticles) had high inhibitory activity on growth of malignant tumor in vivo by uncertain mechanism(s). The activities of enzymes associated with the metabolism of reactive oxygen species [...]