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Analysis of Stem Cell Culture Performance in a Microcarrier Bioreactor System

Ponnuru K., Wu J., Ashok P., Tzanakakis E.S., Furlani E.P., SUNY-Buffalo, US
Human pluripotent stem cells (hPSCs) are capable of differentiating into all somatic cell types and hold great potential for future clinical applications. Recent studies on cell culture in stirred tank bioreactors indicate that mechanical forces [...]

Numerical Analysis of Coupled Particle-Fluid Transport and Free-Flow Magnetic Sorting in Microfluidic Systems

Liu C., Xue X., Furlani E.P., University at Buffalo, US
Magnetic beads are increasingly used in microfluidic systems to selectively separate and sort biomaterial from a specimen for a broad range of biomedical and clinical diagnostic applications. Most theoretical studies of such systems have been [...]

Field-directed and Template-assisted Magnetic Nanoparticle Self-assembly

Xue X., Furlani E.P., SUNY at Buffalo, US
The interest in field-directed assembly of colloidal magnetic nanoparticles has grown steadily in recent years due to a proliferation of applications including targeted drug therapy, biomedical imaging, among others. Such self-assembly holds promise as a [...]

Cell Detection and Discrimination by a Microfluidic-Integrated Broadband Microchamber

Denzi A., Apollonio F., Liberti M., Caterina M., Ning Y., Multari C., Palego C., Cheng X., Hwang J.C.M., Lehigh University, US
In the last years, the development of broadband microwave sensors for cell detection has become a great challenge. In this work, a broadband microchamber integrated with microfluidics is used for cell detection in the GHz [...]

Simple and Accurate Formula for the Electrostatically Actuated Curled Beam Problem

Younis M., SUNY Binghamton, US
We present analytical solutions of the electrostatically actuated initially deformed cantilever beam problem. We use a continuous Euler-Bernoulli beam model combined with a single-mode Galerkin approximation. We derive simple analytical expressions for two commonly observed [...]

A Computational Study on Detection of Ultra Small Volumes of Liquid and Solid Media in Microcavities Using Surface Acoustic Wave Devices

Senveli S.U., Tigli O., University of Miami, US
In this study, we use finite element method (FEM) analysis to show the possibility of a microsystem capable of detecting and analyzing liquid and solid media in minute amounts using surface acoustic wave (SAW) devices [...]

Modeling and Simulation of PVDF-TrFE Based MEMS Scale Cantilever Type Energy Harvesters

Toprak A., Tigli O., University of Miami, US
We present the FEM modeling and simulation of a cantilever type piezoelectric energy harvester constructed using PVDF-TrFE. PVDF-TrFE is a CMOS compatible, soft piezoelectric polymer with a moderate electromechanical coupling coefficient. It is also flexible [...]

Analysis and Simulation of Rare Cell Detection and Size Based Profiling Using Coupled Micro-Hall Detectors

Gajasinghe R.W.R.L., Gabriel A., Tigli O., University of Miami, US
In this paper, we propose a method that uses magnetic nanoparticles (MNPs) to detect, and also estimate sizes of rare cells using Hall-effect. Rare cells labeled with MNPs are detected in-flow using a pair of [...]

Nanomagnet Logic – From Concept to Prototype

Bernstein G.H., Butler K., Li P., Shah F., Siddiq M., Csaba G., Hu X.S., Niemier M., Porod W., University of Notre Dame, US
As the semiconductor industry foresees an inevitable slowing of Moore's Law, many researchers are trying to develop new technologies that go beyond CMOS, in speed, density, cost, or some other desirable metric. Notre Dame has [...]

Flexible Microsensor for Shape Detection

Beharic J., Lucas T.M., Senousy Y.M., Harnett C.K., University of Louisville, US
Modern techniques used in microelectromechanical systems (MEMS) sensor fabrication are adequate for use in most of today’s planar devices, which do not require flexibility to function. However, it’s difficult for a rigid structure to conform [...]

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