US – Page 341 – TechConnect Briefs

DNA/Cellulose hybrid nanomaterials

Mangalam A., Simonsen J., Benight A.S., Oregon State University, US

One potential advantage of nanotechnology is the ability to engineer bottom-up hierarchical assembly of nanoparticles into functional macroscale materials and devices. The most promising mechanism for accomplishing this is self-assembly. In this project, an advanced [...]

3D Microfabricated Bioreactors

Xia C.-G., Fang N., University of Illinois at Urbana-Champaign, US

We present here an innovative three dimensional microfabrication technology that will serve as a vehicle to enable vascularized bioreactors for in vitro tissue culture. The core of our microfabrication technology is a high-resolution projection micro [...]

Transport of Multiple Enzymes through Semipermeable Membrane and Effect of Surfactants

Trigo C., Leung S.W., Bhushan A., Daniels C.K., Lai J.C.K., Idaho State University, College of Engineering, US

Surfactants are known to influence functions of many proteins in membranes, cells and tissues. Because most studies to elucidate the effects of surfactants on membrane-bound proteins and cells employed heterogeneous or complex systems, it is [...]

Nano-Structured Biodegradable Ceramics for the Treatment of Osteoporosis

Balasundaram G., Webster T.J., Purdue University, US

There are a number of applications requiring bone-building agents. For example, osteoporosis is a disease resulting in weak bone. However, no current effective prevention and treatment methods exist for osteoporosis. For these reasons, in this [...]

Stem cell differentiation on nano-structured carbon surfaces

Ercan B., Price R., Webster T.J., Purdue University, US

The research is based on the differentiation of stem cells on carbonnanofibers.

Increased Osteoblast Adhesion on Nano-rough Anodized Titanium and CoCrMo

Yao C., Slamovicha E.B., Webster T.J., Purdue University, US

Titanium and cobalt-based alloys are two main groups of metallic materials widely used in orthopedic applications. One approach to improve biological properties of current titanium and CoCrMo implant is to mimic the nanostructures of natural [...]

Enzymatically Degradable Hydrogel Nanocomposite for Bone Regeneration

Jabbari E., He X., Sarvestani A.S., University of South Carolina, US

One approach to bone replacement involves the use of in-situ crosslinkable scaffolds for cell transplantation to promote tissue growth, nutrient diffusion, matrix production, and vascularization. Bone matrix is a composite material consisting of aqueous and [...]

Nano-Hydroxyapatite Coated Acetabular Cup Implant by Electrophoretic Deposition

Zhang H., Zhang Z., Krajewski J., Zhang H., Zhang Z., Xiao T.D., Reisner D., Inframat Corporation, US

A nanostructural hydroxyapatite (HA) coating was deposited to the porous Ti6Al4V hip cup implant using electrophoretic deposition (EPD) in order to improve the bonding strength between the implants and cells, fast healing, good resistance to [...]

Nanoscale Analysis of Bone Mineral Crystals

Chen H., Robinson C., Shore R.C., Brookes S.J., Zhang J., Smith D.A., Clarkson B.H., Kirkham J., University of Michigan, US

The mineral component of both bones and teeth comprises of crystals of calcium hydroxyapatite. However, there are very few studies which have characterised and compared individual crystals from these mineralised tissues at the nanoscale. In [...]

Less Harmful Acidic Degradation of Poly(lactide-co-glycolide) Bone Tissue Engineering Scaffolds through Titania Nanoparticle Addition

Liu H., Slamovich E.B., Webster T.J., Purdue University, US

In the last ten years, biodegradable aliphatic polyesters, such as poly(lactide-co-glycolide) acid (PLGA), have attracted increasing attention for their use as scaffold materials in bone tissue engineering because their degradation products can be removed by [...]