US – Page 260 – TechConnect Briefs

Micron Particles Segregation in Lower Electric Field Regions in Very Dilute Neutrally Buoyant Suspensions

Qiu Z.Y., Shen Y., Tada S., Jacqmin D., The City College of New York, US

We use a spatially periodical electrode array in a fluid chamber to generate a high gradient electric field. Neutrally buoyant poly alpha olefin particles in corn oil in the chamber are transported to the lower [...]

Modeling Magnetic Transport of Nanoparticles with Application to Magnetofection

Furlani E.P., Ng K.C., University at Buffalo, US

Magnetic nanoparticles are finding increasing use in a broad range of bioapplications, primarily as carrier particles for biomaterials such as cells, proteins, antigens and DNA. The use of biofunctional magnetic particles enables selective immobilization and [...]

Discrete Mixing of Nanoliter Drops in Microchannels

Rhee M., Burns M.A., University of Michigan, US

We present the theory, simulations and experiments for discrete drop mixing in microfluidic systems. The generalized analytical solutions have been derived and confirmed by simulations and on-chip experiments. The discrete drop mixing occurs in three [...]

Integrated Thermal Modulation and Deflection of Viscous Microjets with Applications to Continuous Inkjet Printing

Furlani E.P., Ng K.C., Lopez A.G., Anagnostopoulos C., Eastman Kodak, US

We present a novel CMOS/MEMS microfluidic device that enables the controlled production and redirection of streams of picoliter-sized droplets at frequency rates in the hundreds of kilohertz range. This device consists of a pressurized reservoir [...]

A Novel Parallel Flow Control (PFC) System for Syringe-Driven Nanofluidics

Liang H., Nam W.J., Fonash S.J., The Pennsylvania State University, US

In this work, we introduce the parallel flow control (PFC) configuration shown in Fig. 1 to address these key interfacing and flow control issues. PFC uses flow in a pressure-driven micro-channel, which interfaces with the [...]

Generation of picoliter and nanoliter drops on-demand in a microfluidic chip

Xu J., Attinger D., Columbia University, US

In this work, we introduce the novel technique of in-chip drop-on-demand, which consists in dispensing picoliter to nanoliter drops on demand directly in the liquid-filled channels of a polymer microfluidic chip. The technique involves a [...]

Fluidic and Electrical Characterization of 3D Carbon Dielectrophoresis with Finite Element Analysis

Martinez-Duarte R., Collado-Arredondo E., Cito S., Martinez S.O., Martinez-Duarte R., Madou M., University of California Irvine, US

The following work presents the fluidic and electrical characterization of a 3D electrodes array to be used in high throughput and high efficiency Carbon Dielectrophoresis (CarbonDEP) applications such as multi-stage filters, continuous particle enrichment and [...]

Optimizing Multiscale Networks for Transient Transport in Nanoporous Materials

Nilson R.H., Griffiths S.K., Sandia National Laboratories, US

Hierarchical nanoporous materials afford the opportunity to combine the high surface area and functionality of nanopores with the superior charge/discharge characteristics of wider transport channels. In the present paper we optimize the apertures and spacing [...]

Amperometric glucose sensor for real time extracellular glucose monitoring in microfluidic device

Ges I.A., Baudenbacher F.J., Vanderbilt University, US

Glucose and lactate are the most important metabolites which characterize physiological state and the metabolic activity of living cells. Consequently, development of a stable glucose biosensor is an interesting and important research topic for medicine [...]

Using Microfluidics for Metabolic Monitoring of Single Embryo Cultures

Thorsen T., Urbanski J.-P., Johnson M.T., Craig D.D., Potter D.L., Gardner D.K., Massachusetts Institute of Technology, US

In recent years, microfluidics has demonstrated novel methods of culturing and studying cells. Within well-defined volumes comparable to the sample of interest, media, nutrients or toxins may be precisely targeted to individual cells via diffusion [...]