US – Page 153 – TechConnect Briefs

SUEX for High Aspect Ratio Micro-Nanofluidic Applications

Johnson D., Goettert J., Singh V., Yemane D., DJ DevCorp, US

Microfluidics applications can benefit from a dry film approach in multiple ways – particularly in the preparation of multi-layer, multi-level fluidic channels and structures on patternable substrates and covers. In addition, polymer microreactors and other [...]

A Novel Compact Lab-on-a-Chip Nanosensor for In-Channel Liquid Viscosity Detection

Zhao J., Xu J., Xue W., Xue W., Washington State University Vancouver, US

Real-time monitoring of liquid’s viscosity has significant impacts on many areas such as medicine, biology and petrochemistry. However, most existing sensors have complicated fabrication and testing processes and are not truly compatible with fluidic systems [...]

Single-cell manipulation using Nanopipettes

Maalouf M.M., Jain M., Actis P., Pourmand N., University of California, Santa Cruz, US

Manipulation and analysis of individual cells is key in understanding processes that control single-cell behavior in complex environment. Nanotechnology-based tools having high sensitivity and low invasiveness are holding great promises as new biomedical devices for [...]

Uncoil long DNA molecules in nanoposts array

Wu J., Shao G., Choi J., Uba F.I., Soper S.A., Park S., Louisiana State Univ., US

A nanoposts array was fabricated on a PMMA based nanofluidic chip by nanoimprinting lithography. The electrophoresis of Lambda and T4 DNA in the nanoposts was studied. A periodical stretching and recoiling motion was observed. Each [...]

Free-Surface Microfluidics: Exploring New Actuation and Sensing Methods

Yu G., Lei N., Chen X., Xue W., Xu J., Xue W., Washington State University, US

Unlike traditional microchannel-based microfluidics, free-surface microfluidics features no channel, ease to clean, simple design fabrication and operation, as well as external access to the samples. It has been proven that free-surface droplets can be actuated [...]

Atomistic Simulations of Biomolecules at the Water‐Amorphous Silica Interface: Application to Peptides and DNA Oligomers

Shi B., Shin Y.K., Shin Y.K., Hassanali A., Singer S.J., Ohio State University, US

Realistic modeling of biomolecules near amorphous silica (“glass”), a material commonly used for biomedical device fabrication, is required for device design and evaluation. Our potential model, based on ab initio quantum chemical calculations, is designed [...]

Modeling Fluid Structure-Interactions for Biomechanic Analysis of the Human Eye

Furlani E.P., Nunez A., Vizzeri G., University at Buffalo (SUNY), US

The human eye is a highly complex organ that consists of multiple different tissues with different properties and functionality, as well as pressurized fluid compartments with limited flow. Owing to this complexity, there are many [...]

Electrothermal blinking vortices for chaotic mixing

Kauffmann P., Loire S., Mezic I., UCSB, US

At microscale, an efficient mixing is a keystep which dramatically accelerates bio-reactions. This paper presents an experimental and theoretical study of electrothermal chaotic mixing. To do so, asymmetric vortices are blinked to perform time dependant [...]

Microfluidic manipulation of Caenorhabditis elegans using acoustic radiation forces

Yu G., Chen X., Xu J., Washington State University, US

The ability to precisely trap, transport and manipulate micrometer-sized objects is very important in microfluidic applications. Caenorhabditis elegans (C. elegans) is one of the most commonly used animals in biological and medical research due to [...]

Additive Manufacturing (AM) of Quantum Dot Nano-Inks

Ivanova O.S., Elliott A., Campbell T.A., Williams C.B., Virginia Tech, US

Additive Manufacturing (AM) pertains to technologies that fabricate 3D artifacts through the successive addition of 2D cross-sectional layers. Due to this layer-by-layer fabrication process, AM allows a designer to create geometrically complex artifacts with designed [...]