JP – Page 29 – TechConnect Briefs

Nanomachining on Si (100) Surfaces Using an Atomic Force Microscope with Lateral Force Transducer

Ichida Y., Morimoto Y., Sato R., Murakami M., Utsunomiya University, JP

In recent years, the surface modification with an atomic force microscope (AFM) has attracted special interest as one of the surface processing techniques in a nanometer scale [1-3]. Particularly, this technique will play an increasingly [...]

Introduction of Micro-Manipulation by Adhesional Force and Dielectric Force

Takahashi K., An Y., Saito S., OnzawaTadao T., Tokyo Institute of Technology, JP

This paper reports the manipulation by both adhesional force and Coulomb force. Applicability of this method is discussed evaluating both of the forces theoretically and experimentally. Adhesional force can be used as attractive force in [...]

Development of the Multi-pixel X-ray Microcalorimeters

Kudo H., Nakamura T., Arakawa T., Ohtsuka S., Izumi T., Shoji S., Sato H., Kobayashi H., Mori K., Morita U., Homma T., Osaka T., Mitsuda K., Yamasaki N.Y., Fujimoto R., Iyomoto N., Oshima T., Futamoto K., Takei Y., Ichitsubo T., Fujimori T., Ishisaki Y., Morita U., Ohashi T., Kuroda Y., Onishi M., Otake K., Waseda University, JP

We are developing a multi-pixel x-ray microcalorimeters in order to realize good energy resolution x-ray imaging for future Japanese X-ray astronomy missions. The energy resolutions of 10eV at 6keV and 32x32 pixels of arrayed x-ray [...]

Modeling of Surface Tension in Fluidic MEMS Using the Level-Set Method

Takahashi K., Kyushu University, JP

Mixed state of liquid and gas is frequently seen in fluidic MEMS, for example, ink jet printer, heat exchanger, thermo-capillary optical switch, and so on. The surface tension is the most dominant mechanical effect in [...]

Visualization of Fluidic and Reaction Dynamics in Microchannels

Kawazumi H., Muraki A., Kanno K., Maeda H., Kinki University, Kyushu, JP

An easy-to-use and low cost microreactor made of polymethylmethacrylate was mechanically fabricated with a microchannel. The laminar flow behavior was investigated by visualizing the flow of red and green aqueous solutions. Digitized color images from [...]

Highly Integrated Transparent Microchannel Chips for Continuous-flow PCR

Sun K., Matsuo S., Misawa H., Satellite Venture Business Laboratory, The University of Tokushima, JP

A microchannel chip for continuous-flow polymerase chain reaction (PCR) was developed using transparent materials. The microchannel was fabricated on a quartz glass substrate using standard photolithography and wet-etching techniques, and was sealed by another quartz [...]

Replica Exchange Molecular Dynamics Toolkit for Drug-receptor Docking

Ito M., Nishikawa T., Nagashima U., National Institute of Advanced Industrial Science and Technology, JP

In this post-genomic era, much attention is focused on the 3D structure and flexibility of protein molecules for the rational drug design. Although the structure information provides a good starting point for estimating the ligand-protein [...]

CONFLEX: Conformational Behaviors of Polypeptides as Predicted by a Conformational Space Search

Goto H., Takahashi T., Takata Y., Ohta K., Nagashima U., Toyohashi University of Technology, JP

The elucidation of the stable conformations and the folding process of proteins is one of the most fundamental and challenging goals in life science. While some of the most common secondary structures (e.g., a few [...]

Mathematical Modeling the Dynamics of Recombinant Endonuclease Production in Microsystems

Ohtaguchi K., Asami K., Tokyo Institute of Technology, JP

A mathematical model for the dynamics of micro-scale production of recombinant human DNase I is formulated. In experiments extracellular production of human DNase I gene product from methylotrophic yeast Pichia pastoris GS115 has been achieved. [...]

Structuring Knowledge Project in Nanotechnology Materials Program – Construction of the Knowledge Infrastructure for Nano-materials and Devices

Kitao O., Yamaguchi Y., Watanabe E., Yano Y., Yasuda H., Miyahara M., Adschiri T., Ogawa T., Komiyama H., The University of Tokyo, JP

The Ministry of Economy, Trade, and Industry, JAPAN has just launched a long-term national program on nanotechnology materials (NMs). This program consists of 8 projects (PJs), and “Structuring Knowledge (SK)” PJ plays an extremely important [...]