Biomaterials – TechConnect Briefs

Bioabsorbable Anti-inflammatory Material: A Novel Protein-Conjugated Polymer with Applications in the Implantable Medical Device Field

Rapier C.E., Chen E., Liu W.F., Lee A.P., University of California Irvine, US

Biodegradable/bioabsorbable materials are a relatively new movement in the implantable medical device field. Despite the promise of non-permanent implants, bioabsorbable materials can induce a localized inflammatory immune response. To overcome this limitation, we are combining [...]

Adsorption of Cd (II) Ions from Aqueous Solution Using Activated Carbon Prepared from Vitellaria paradoxa Shell

Adebayo G.B., Adekola F.A., Jimoh A.A., Alao F.O., Adegoke H.I., University of Ilorin, NG

Activated carbon prepared from vitellaria paradoxa shell using ortho-phosphoric acid as activating agent was used for the removal of Cd (II) ions from aqueous solution. The adsorbent sample was characterized by some physicochemical and spectroscopic [...]

Rapid prototyping bacterial spore hygro-actuators for soft robotics and adaptive materials

Cavusoglu A.‐H., Chen X., Tatem K., Sahin O., Columbia University, US

Over the past decade, rapid prototyping has migrated from the research and industrial labs into the homes of consumers. However, these solid models are limited in demonstrating dynamic actuation. A large range of soft materials [...]

Microbial-mediated Au@biolayer core-shell nanoparticles: synthesis and application

Liu W.J., Jing C.Y., Chinese Academy of Science, CN

Gold nanoparticles (Au NPs) bio-synthesized through microbial activities create biocompatible and non-toxic nanomaterials that may have great applications in analysis, catalysis, and biomedicine. Herein, we demonstrated that Pantoea sp. IMH can generate Au@biolayer core-shell nanoparticles. [...]

Bio-inspired Polydopamine Treatment and Nanosilver Formation for Antibacterial Uses

Chiu Y.-H., Li M.-C., Wu K.-M., Chung Y-C, National University of Kaohsiung, TW

In the study, we employed the mussels’ glue component—dopamine and its excellent reducing ability toward silver ions, to create a novel antibacterial effect on a facial mask surface so as not to add harmful antiseptics [...]

Three-Dimensional Macroporous Carbon Nanotube Scaffolds for Stem Cell Expansion and Maintenance

Lalwani G., Gopalan A., D’Agati M., Patel S., Talukdar Y., Sitharaman B., Stony Brook University, US

Expansion of stem cells and maintenance of their self-renewal capacity in vitro requires specialized robust cell culture systems. Conventional approaches consisting of animal derived matrices and cocktail of growth factors have limitations such as consistency, [...]

One and two dimensional inorganic nanoparticles’ interactions with fibroblasts and stem cells

Rashkow J.T., Talukdar Y., Lalwani G., Sitharaman B., Stony Brook University, US

We report the effects of one and two dimensional transition metal dichalcogenide nanoparticles, tungsten disulfide nanotubes (WSNTs) and molybdenum disulfide nanoplatelets (MSNPs), on fibroblastic cell (mouse fibroblasts (NIH-3T3) and human adipose derived stem cell (MSC)) [...]

Preparation and investigation of nano- carbonated hydroxyapatite/polymer composite spongy scaffolds for biomedical applications

Siddiqi S.A., Manzoor F., Azhar U., Jamal A., Tariq M., Anwar M.S., Saleem M., Chaudhry A.A., Rehman I.U., COMSATS Institute of Information Technology, PK

Spongy scaffolds containing nano-Carbonated Hydroxyapatite (nCHA), with composition Ca10(PO4)6-y(CO3)y(OH)2,with y=2,4, were prepared by the lyophilization method. Different polymers, natural gelatin (G), chitosan (CS) and polyvinyl alcohol (PVA), alone or in combination, were used to make [...]

Electrophoretic Coating of Hydroxyapatite-Boron Nitride Nanocomposites on Titanium Implants

Bakan F., Sezen M., Goncu Y., Ay N., Sabanci University, TR

Titanium (Ti) and its alloys have long been used as implant materials in dental and orthopedic applications. However, they can suffer certain disadvantages, such as poor osteoinductive properties and low corrosive-wear resistance. The potential of [...]

Nonclinical evaluation of heparin binding copolymer – HBC1 for restoring of blood coagulation after heparin treatment

Kalaska B., Sokolowska E., Kaminski K., Miklosz J., Shin-ichi Y., Błazejczyk A., Wietrzyk J., Kasacka I., Szczubialka K., Pawlak D., Nowakowska M., Mogielnicki A., Medical University of Bialystok, PL

The incredible progress and wide use of various medical devices during intravascular or cardiac interventions increased the need for administration of anticoagulants, such as heparins. Protamine sulfate – a protein isolated from salmons is the [...]

Dex40-GTMAC3, modified dextran as a novel heparin antagonist

Kalaska B., Kaminski K., Sokolowska E., Czaplicki D., Kujdowicz M., Stalinska K., Szczubialka K., Bereta J., Pawlak D., Nowakowska M., Mogielnicki A., Medical University of Bialystok, PL

Protamine is the only registered antidote preventing bleeding of patients treated with unfractionated heparin (UFH). However protamine may induce anaphylactic shock or serious hypotension. We aimed to develop an alternative fully synthetic UFH antidote as [...]

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