Papers:
Replica Exchange Molecular Dynamics Toolkit for Drug-receptor Docking
Ito M., Nishikawa T., Nagashima U., National Institute of Advanced Industrial Science and Technology, JP
In this post-genomic era, much attention is focused on the 3D structure and flexibility of protein molecules for the rational drug design. Although the structure information provides a good starting point for estimating the ligand-protein [...]
Freeze-fracture Electron Microscopy on Nanostructures for Drug & Gene Delivery
The potency of drug/gene-loaded carriers is frequently depending upon their morphology adopted in a biological relevant environment. Freeze-fracture electron microscopy/1/ is not only a powerful technique to characterize drug/gene carrier on a nanometer resolution scale/2,4-11/ [...]
Stochastic Tunneling Method for High Throughput Database Screening
Virtual screeing of large databases of chemical compounds against known structurally resolved protein receptors emerges as a promising route for lead discovery in drug design. In this approach each ligand of the database is aligned [...]
Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2003 Nanotechnology Conference and Trade Show, Volume 1
Published: February 23, 2003
Industry sector: Medical & Biotech
Topic: Biomaterials
ISBN: 0-9728422-0-9