Micro & Bio Fluidics, Lab-on-Chip – Page 26

Combining Additive and Substractive techniques in the design and fabrication of Microfluidic devices

Levine L., ALine, Inc., US

Laminate construction of microfluidic devices offers a means to adopt both additive and subtractive manufacturing techniques for the development and manufacture of multiplexed fluidic devices that have porous membranes formed in-situ for applications in sample [...]

New sample injection methods for chip electrophoresis

Gaspar A., Piyasena M., Gomez F.A., California State University Los Angeles, US

Electrokinetic injection is commonly utilized in capillary chip electrophoresis (CE) even though mobility and matrix bias makes quantitation difficult. Hence, injection techniques that provide for both reproducible and precise injection of sample are warranted. Herein, [...]

Design & Fabrication of Ceramic Microarrays Using Powder Injection Molding

Atre S.V., Wu C., Park S-J, Simmons K., Oregon Nanoscience & Microtechnologies Institute, US

Microsystem technology has propelled the development of micro and multi-scale manufacturing techniques for more than a decade. Among these techniques, micro powder injection molding is drawing attention recently as one of the most cost-effective processes [...]

Control of Micro-Fluidic Flow using 3D Features

Bullock L.E., Robinson A.E., University of Massachusetts Dartmouth, US

Lab-on-a-Chip sensors require precise control and mixing of samples, reagents and buffers. This paper will present new techniques for using Excimer Laser, micro-machined, three-dimensional (3D) channel and well features to pump and control fluids in [...]

200um-class Polymeric Microneedle Fabricated by a Micro Injection Molding Technique

Kang J-J, Lee S-H., Jung T-S, Heo Y-M, Korea Institute of Industrial Technology, KR

Extensive microneedle research has been conducted to enhance the efficiency of transdermal drug delivery. It has been expected and shown through experiments in vivo that microneedles can increase the skin permeability to deliver drugs by [...]

Using epoxy resin to fabricate a master for microfluidic devices in poly(dimethylsiloxane)

Pan Y-J, Yang R-J, National Cheng Kung University, TW

This paper presents two methods for the production of UV epoxy resin masters for the replication of PDMS-based microfluidic chips. The epoxy resin master can be either fabricated by using a negative glass template which [...]

A Microfluidic Device for Opto-Electrochemical Sensing

Luo T.-J.M., Choi Y., Huh U., North Carolina State University, US

To integrate functionality of transmembrane proteins to devices, a platform compatible with proteins and phospholipids membrane is required. In our effort to address the needs for current and future research, we report a microfluidic device [...]

Three-Dimensional Transient Motion of Spherical and Deformable Droplet in L-Shaped Rectangular Microchannel

Kang C.W., Hua J.S., Lou J., Institute of High Performance Computing, SG

Three-dimensional transient motion of spherical and small deformable droplet in an L-shaped rectangular channel is investigated numerically. The methodology employed is front tracking coupled with the parallel adaptive refinement meshing code, referred as PARAMESH. The [...]

Simulation on biological cell transport in the microfluidic devices

Kim M.C., Wang Z.H., Lam R.H.W., Thorsen T., Massachusetts Institute of Technology, US

We have developed a Bio-Particle (BP) simulation technique for the general particle movement in Lab-On-A-Chip devices. This has also been validated with experiments on biological cells (3T3 cell; diameter 10 μm). The cell motion under [...]

A Microsystem and Model for Continuous Immunomagnetic Cell Sorting

Furlani E.P., University at Buffalo (SUNY), US

We present a microsystem concept and mathematical model for the continuous sorting of magnetically labeled cells. The microsystem consists of two inlets, two partially connected microchannels, and two outlets. A soft-magnetic element is positioned beneath [...]