Medical & Biotech – Page 175 – TechConnect Briefs

MEMS Biofluidic Device Concept Based on a Supramolecular Motor

Knieser M.J., Knieser M.R., Pidaparti R., Kadioglu F., Harris R.D., Knieser M.J., Knieser M.R., Hsu A., Indiana Univerisity Purdue University Indianapolis, US

The supramolecular machine, called the nuclear pore complex (NPC), controls the transport of all cellular material between the cytoplasm and the nucleus that occurs naturally in all biological cells. In the presence of appropriate chemical [...]

Biomimetic Molecules as Building Blocks for Synthetic Muscles – A Proposal

Flood A.H., Badjic J., Han J-Y, Pentecost C., Northrop B.H., Cantrill S.J., Houk K.N., Stoddart J.F., UCLA and CNSI, US

Biomolecular motors are natures machines that convert chemical energy into mechanical work. The performance and scale of these systems are believed to derive from their precise positioning and alignment into organized hierarchical levels at the [...]

Viral Protein Linear (VPL) Nano-Actuators

Dubey A., Sharma G., Mavroidis C., Tomassone S.M., Nikitczuk K.P., Yarmush M.L., Northeastern University, US

The Bio-Nano-Robotics Group at Rutgers is interested in achieving efficient motion/energy conversion through nanoscale mechanical devices made from biomolecules, such as proteins and DNA, in tandem with synthetic devices such as carbon nanotubes. In a [...]

A Molecular Motor that Links the Biological and Silicon Worlds

Robinson T., Blundell A., Dutta C.F., Firman K., University of Portsmouth, UK

The EcoR124I restriction endonuclease is also a biological molecular motor. It is able to attach to DNA at a specific location and then translocate the rest of the DNA molecule through the bound complex. Therefore, [...]

Actin Adsorbed on HOPG and Mica Substrates: Characterization and Manipulation by Atomic Force Microscopy

Nicolau D.V., Watson G.S., Cahill C., Blach J., Myhra S., Swinburne University, AU

We report on the fabrication of nanostructures built of actin using the Atomic Force Microscopy and molecularly organised substrata, i.e. HOPG and mica. We obtained both ‘paracrystalline rafts’ of actin adsorbed onto hydrophobic HOPG, as [...]

Bio Molecular Motors

Evaluation of Electric Impedance Spectra for Single Bio-Cells with Microfluidic Devices using Combined FEMLAB/HSPICE Simulated Models

Senez V., Yamamoto T., Poussard B., Fukuba T., Capron J.M., Fujii T., LIMMS/CNRS-IIS - University of Tokyo, JP

This paper describes a simple method to predict the electrical impedance spectrum of single & cultured cells in micro-devices. It can be used for the rapid design of micro-sensors as well as for more fundamental [...]

Sector: Medical & Biotech