Advanced Materials & Manufacturing – Page 585

Numerical Modelling of a Microfluidic Ultrasonic Particle Separator

Townsend R.J., Hill M., Harris N.R., White N.M., Beeby S.P., University of Southampton, UK

Particles held in a fluid suspension and within an acoustic standing wave experience an acoustic radiation force. The force causes particles to move to the pressure nodes of the acoustic field creating a concentrate, contributing [...]

Strong DC and Low-Frequency AC Fields for the Manipulation of Particles and Fluids in Microfluidics

Kumar A., Qiu Z., Khusid B., Yeksel M., Acrivos A., New Jersey Institute of Technology, US

Electroosmosis and electrophoresis are considered to be the main phenomena for transport of aqueous liquids and particles in microfluidic devices because field-based techniques do not require any moving parts and can be incorporated more favorably [...]

A Microfluidic System for Continuous Magnetophoretic Separation of Suspended Cells Using Their Native Magnetic Properties

Han K-H, Bruno Frazier A., Georgia Institute of Technology, US

This paper presents the characterization of a continuous magnetophoretic microseparator for separating white and red blood cells from whole blood by using a high gradient magnetic separation method and microfabrication technology. The magnetophoretic microseparator directly [...]

Biomimetic Design of a Microfluidic Device for Auto-separation of Leukocytes from Whole Blood

Shevkoplyas S.S., Yoshida T., Munn L.L., Bitensky M.W., Boston University, US

Leukocytes comprise less than one percent of all blood cells. Enrichment of their number, starting from a sample of whole blood, is the required first step of many clinical and basic research assays. We created [...]

Highly Selective Capture and Transport of Rare Cells in Microfluidic Channels

Ward M.D., Grodzinski P., Los Alamos National Laboratory, US

Collection of rare target cells in clinical samples such as disseminated tumor cells in peripheral blood or fetal cells in maternal blood poses difficult challenges to currently available cell separation methods. A novel, two stage [...]

Bio Nano Particles

Electronic Sensing of Antibodies using Carbon Nanotube Devices

Teker K., Sivakumar K., Wickstrom E., Panchapakesan B., University of Delaware, US

Carbon nanotubes (CNTs) are remarkable solid state nanomaterials due to their unique properties such as high surface area, hollow cavities, and excellent mechanical and electrical properties. Interfacing carbon nanotubes with biological materials could enable significant [...]

Optimal Design of Laser Surgery for Cancer Treatment Through Nanoshell-Mediated Hyperthermia Therapy

Feng Y., Rylander N., Bass J., Oden J.T., Diller K., The University of Texas at Austin, US

Recent development of nanoparticle technology and its application in hyperthermia therapies makes it possible to consider optimal control of the temperature field and thermal energy delivered to the tumor region with minimal destruction of surrounding [...]

Photo-Enhanced Luminescence in Bio-conjugated Quantum Dots for Ovarian Cancer Biomarkers

Dybiec M., Korsunska N.E., Zhukov P., Zhukov T., Ostapenko S., Sellers T., Zajac A., Zhukov P., Zhukov T., University of South Florida, US

Ovarian cancer is the most lethal gynecologic malignancy. This largely reflects the fact that approximately 75% of cases are detected at advanced stages of disease, when cure is unlikely. In contrast, 5-year survival for patients [...]

The Evolution of Vievs of in vivo Use of Nanoparticles for Tumor Treatment

Chissov V.I., Reshetov I.V., Luskinovich P.N., Shepelev A.A, Efremov G.D., Matorin O.V., Sukharev S.S., P.A.Hertsen Moscow Research Oncological Institute (MROI), RU

The methods of site-specific delivery of antitumor agents without the general and system consecuences remain to be actual because the need to reduce the negative effects of antitumor treatment. In the experiment attempts are made [...]