Ion channels play a crucial role in the physiology of complex biological systems because of their influence on the electrical equilibrium between the cells and their environment. From an engineering viewpoint, ion channels will be the key components of the design and the production of a new generation of biosensors integrating the selectivity of ion channels with the processing capabilities of modern microelectronics. The aim of this contribution is to review the state-ofthe-art simulative approaches used for the modeling ofthe ion channel environment. Aself-consisten t approach will be presented, based on the coupling of Poisson/Coulomb/Langevin solvers, and aimed to model the dynamics of ionic solutions. Simulation results will be shown as well.
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2002 International Conference on Computational Nanoscience and Nanotechnology
Published: April 22, 2002
Pages: 52 - 55
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech