Structural Genomics and Automated X-ray Crystal Structure Solution

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Rapid advances in genomic sequencing are changing the focus and pace of structural biology, shifting from a reductionist approach to a broad view of all the pieces that come into play in a cell or organism. Here we describe how structural information can be obtained in an efficient fashion suitable for genomic-scale structural analyses and discuss recent developments in automation of crystallographic software that will help allow high-throughput structure determination become a reality.

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Journal: TechConnect Briefs
Volume: Technical Proceedings of the 1999 International Conference on Modeling and Simulation of Microsystems
Published: April 19, 1999
Pages: 42 - 44
Industry sector: Medical & Biotech
Topics: Biomaterials, Informatics, Modeling & Simulation
ISBN: 0-9666135-4-6