Penn S., Cromer R., Sha M., Doering B., Brown B., Norton S., Walton I.
Oxonica Inc, US
Keywords: blood, diagnostics, multiplex, nanoparticle, raman, sers
Oxonica Inc has developed a novel optical detection tag for use in point of care diagnostics, cellular imaging assays, and life science assays. Nanoplex(TM) Biotags are silica coated Au nanoparticles that, by virtue of surface enhanced Raman scattering (SERS) active molecules at the glass-metal interface, act as detectable tags. Many unique tags can be generated by varying the Raman active molecule adsorbed on the nanoparticle, thus allowing multiplexed detection to be performed. Importantly, because the tags are excited in the far red or near-IR, and can be detected with low-cost instrumentation, they are ideal for performing assays in both tissue and whole blood. We will present data showing the versatility of this novel nanotechnology, and the applications to diagnostics.
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 20, 2007
Pages: 447 - 448
Industry sector: Sensors, MEMS, Electronics
Topics: Biomaterials, Chemical, Physical & Bio-Sensors
ISBN: 1-4200-6183-6