Patchan M., Calderon-Colon X., Benkoski J., Theodore M., Le H., Fuller B., Boggs N., Nelson A., Garza L., Sarkar K., Brandacher G., Patrone J.
The Johns Hopkins University Applied Physics Laboratory, US
Keywords: bandage, cellulose, drug delivery, nanoparticle
Burn injuries, trauma, and surgical procedures result in complex wounds, which can lead to pain, infection, and scarring. Management of complex wounds remains a critical challenge for the medical community and effective, localized treatments are limited. Recent advancements in nanotechnology offer a unique opportunity to deliver therapeutics to wounds and improve healing. The goal of our work is to combine nontoxic, biodegradable nanomaterials with therapeutics in order to design a topical drug delivery system for controlled release into skin. In this study we demonstrate the potential of combining solid lipid nanoparticles (SLNs) and bacterial cellulose into a novel system for controlled topical drug delivery.
Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2013: Bio Sensors, Instruments, Medical, Environment and Energy (Volume 3)
Published: May 12, 2013
Pages: 255 - 258
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 978-1-4822-0586-2