Meymanat M.
Zanjan University of Medical Sciences, Zanjan, Iran, IR
Keywords: cancer detection, cancer treatment, Electromagnetic induction, ferromagnetic nano-particle, Nano-targeting
A Biofunctionalized conductor Nano-Particle which can be made of ferromagnetic and conductor materials, capable to attach specifically biologic targets in vivo and in vitro by using molecules for specific attachment (such as monoclonal antibody) is proposed in this method. An external alternative magnetic inductor causes inductive electric, magnetic and thermal effects in above particles near target which can be malignant cell membrane, bio-molecules, bacterial cell wall or viral capsid. Since the physical balance is critical for biologic systems, any physical irregularity can potentially cause target devastative effects controllable from dysfunction to destruction. Since the magnetic force-lines penetrate deep in tissues, and nano components flow through blood to all tissues, deeply sited targets such as bone marrow malignancies will be affected, unlike some new methods which affect only superficial tumors. Here in proposed alternative magnetic field, cases fewer side effects than UV, which is used recently. As the nano-particles are detectable by using MRI, they will show the concentration location of targets this method can be used to both detect and treat various medical complications including cancer. Since there are no toxic medicines or materials used, the risk for normal cell damage, systemic side effects and toxicity is reduced to minimum.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational & Photonics
Published: June 15, 2014
Pages: 375 - 378
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Materials for Drug & Gene Delivery
ISBN: 978-1-4822-5827-1