Lee M., Loo C., Gobin A.M., West J., Halas N., Drezek R.
Korea Electronics Technology Institute, KR
Keywords: nanoshells, OCT
Scattering-based optical imaging technologies such as Optical Coherence Tomography (OCT) and Reflectance Confocal Microscopy (RCM) offer a unique non-invasive approach to the detection, diagnosis, and monitoring of cancer. In this article, we describe the use of targeted NIR-tuned gold nanoshell for imaging in vitro, ex vivo and in vivo. Nanoshells are a new class of optically active nanoparticles with tunable plasmon resonances based on geometric construction. These particles can be easily tuned to absorb or scatter strongly within the wavelengths of 650-1300 nm, known as the near infrared region. This region is of significant biological importance providing a therapeutic window and imaging applications in tissue as the primary components of tissue, blood and water, do not have significant absorption coefficients in this range of wavelengths
Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2007 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 20, 2007
Pages: 306 - 309
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topics: Biomaterials, Materials Characterization & Imaging
ISBN: 1-4200-6183-6