Combining the advantages of the structural, chemical, and lyotropic properties of membrane lipids with the nanostructuring capabilities of dip-pen nanolithograpy (DPN), makes possible creation of semisynthetic functional lipid nanostructures. Two examples of critical dimensions that are important to consider in determining size-dependent functions are: 1. The size of an individual cell (~1–100 micrometers) 2. The wavelength of visible light (~380–750 nanometers) The ability for phospholipid-based DPN to pattern biofunctional lipids across these scales opens the possibility of using subcellular patterns for biological studies of cell adhesion, as well as biophotonic structures for label-free investigation of liposome function and biosensing.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2010: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational
Published: June 21, 2010
Pages: 227 - 230
Industry sector: Advanced Materials & Manufacturing
Topicss: Advanced Manufacturing, Nanoelectronics