Focused Transcranial Magnetic Stimulation

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Transcranial Magnetic Stimulation is a non-invasive technique used to regulate the synaptic activity of neurons, improving the functionality of several regions and bringing effective treatment to neurological and psychiatric disorders applying external time-varying magnetic fields to superficial regions of the brain, but most of [1], [2] . These conditions can be treated by them originate in deeper areas [3]–[5] . The stimulation of small areas in animals like rodents is not easy, since most of the studies in TMS use commercial equipment for human, with power and coil geometries not designed for small animals. This work presents the design and evaluation of a customized conical coil with a MnZn ferrite core areas as small as 2mm of radius using finite element analysis with ANSYS Maxwell software. Three scenarios of tip sharpening are evaluated at the average lambda-bregma distance in [6], [7] to increase the focality in adult mice, through a novel definition of focality that shows the effectiveness of the coil to perform in vivo experimentation on rodents.

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Journal: TechConnect Briefs
Volume: TechConnect Briefs 2021
Published: October 18, 2021
Pages: 150 - 152
Industry sector: Medical & Biotech
Topics: Biomaterials, Diagnostics & Bioimaging
ISBN: 978-0-578-99550-2