In this study, we developed a novel technique called magnetic hydrogel-based cell patterning (MHCP) to easily achieve heterotypic cell patterning in both of multi-well plate-based methods and microfluidic system. We also demonstrated that the material of magnetic hydrogel and the processes of MHCP produced negligible effects on cell viability. The 2-D heterotypic cell patterning and layer-by-layer 3-D tissue reconstruction could be applied as more complex models in disease research models and tissue engineering.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational
Published: June 13, 2011
Pages: 532 - 534
Industry sectors: Advanced Materials & Manufacturing | Sensors, MEMS, Electronics
Topics: Micro & Bio Fluidics, Lab-on-Chip