Evaluation of Antibacterial Activities of Zinc Oxide-Titanium Dioxide Nanocomposites Prepared by Sol-Gel Method

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Antibacterial activity of ceramic powders has attracted attention as a new technique that can substitute for conventional methods using organic agents. Ceramic powders of zinc oxide (ZnO), calcium oxide (CaO) and magnesium oxide (MgO) were found to show marked antibacterial activity. In the present work, nanocomposites containing nano particle zinc oxide (average size 20 nm) in titanium dioxide (titania) sol-gel matrix has been synthesized with various loading weight percentage of nano zinc oxide powder with respect to titania sol weight. After the nanocomposites were dried into flakes, they were characterized using electron microscopy and x-ray diffractometer to analyse the structure and morphology of the nanocomposites. Bioactivity of the nanocomposites with various Zinc Oxide nano particles weight percentage was studies against Staphylococcus Aureus and Escherichia Coli by conductimetric assay. Nanocomposites with 20wt% and 30wt% of ZnO nanoparticles in TiO2 solgel matrix (will be refer as TiO2-ZnO20 and TiO2-ZnO30 respectively) inhibited 40 to 95% of both antibacterial proliferation from different batch of nanocomposite products. Both nanocomposites selectively inhibit towards E.Coli compare with S.Aureus. A clear dose-dependent response between TiO2-ZnO20 and TiO2-ZnO30 was recorded in S. Aureus assay.

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Journal: TechConnect Briefs
Volume: 1, Nanotechnology 2008: Materials, Fabrication, Particles, and Characterization – Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: June 1, 2008
Pages: 811 - 814
Industry sector: Advanced Materials & Manufacturing
Topics: Nanoparticle Synthesis & Applications
ISBN: 978-1-4200-8503-7